All Covid-19 vaccines work against Indian strain, says WHO chief scientist

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World Health Organisation (WHO) chief scientist Soumya Swaminathan has clarified that the so-called double mutant Indian variant of coronavirus is not resistant to vaccines.</p>
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The top WHO official said in an interview on CNBC that there is "no data" which suggests that the B.1.617 variant of coronavirus is capable of evading the immunity provided through the vaccines.</p>
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Speaking on the efficacy of vaccines available in India, she said , “There is no data to show that double mutant is vaccine resistant. All the available vaccines today in India and elsewhere prevent severe disease and death even if you get the infection. You are not going to end up in the ICU critically ill. The message is please take the vaccine, whichever is available, if you are eligible for it.”</p>
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Meanwhile, the WHO said on Wednesday that the B.1.617 variant of Covid-19, first found in India in October, had been detected in more than 4,500 samples uploaded to an open-access database "from 44 countries in all six WHO regions".</p>
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"And WHO has received reports of detections from five additional countries," it said in its weekly epidemiological update on the pandemic.</p>
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Outside of India, it said that Britain had reported the largest number of Covid cases caused by the variant.</p>
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Earlier this week, the WHO declared B.1.617 — which counts three so-called sub-lineages with slightly different mutations and characteristics — as a "variant of concern".</p>
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It was therefore added to the list containing three other variants of Covid-19 — those first detected in Britain, Brazil and South Africa.</p>
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The variants are seen as more dangerous than the original version of the virus because they are either being more transmissible, deadly or able to get past some vaccine protections.</p>
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<strong>More contagious</strong></p>
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The WHO explained Wednesday that B.1.617 was added to the list because it appears to be transmitting more easily than the original virus, pointing to the "rapid increases in prevalence in multiple countries".</p>
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WHO also pointed to "preliminary evidence" that the variant was more resistant to treatment with the monoclonal antibody Bamlanivimab, and also highlighted early lab studies indicating "limited reduction in neutralisation by antibodies".</p>
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It stressed, though, that "real-world impacts" on the effectiveness of vaccines against the variant for instance "may be limited".</p>
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WHO said the spread of B.1.617, alongside other more transmittable variants, appeared to be one of several factors fuelling India's dramatic surge in new cases and deaths.</p>
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"WHO found that resurgence and acceleration of Covid-19 transmission in India had several potential contributing factors, including increase in the proportion of cases of SARS-CoV-2 variants with potentially increased transmissibility," the report said.</p>
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It also pointed to "several religious and political mass gathering events which increased social mixing; and, under-use of and reduced adherence to public health and social measures".</p>
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"The exact contributions of each of these factors on increased transmission in India are not well understood," the report said.</p>
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WHO stressed that so far, only 0.1 percent of positive Covid tests in India had been genetically sequenced and uploaded to the GISAID database to identify the variant in question.</p>
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By the end of April, B.1.617.1 and B.1.617.2 accounted for 21 and seven percent respectively of all sequenced samples from India, it added.</p>